Last month, Heritage Auctions withdrew original artwork for the 1964 comic book from an auction. Plastino had found it on display at New York Comic Con in October.
Plastino drew the comic and had thought "Superman's Mission for President Kennedy" in "Superman" No. 170 was donated to Boston's Kennedy library decades ago. Heritage says the initial seller of the art had bought it in 1993.
Plastino died late last month at age 91. His wife says she welcomes Monday's move by DC, noting the art was very special to him and their family.