Salido (41-12-2) had winning scores of 116-112 and 115-113, and the third judge scored it 115-113 for Lomachenko. Lomachenko, from the Ukraine, could have won the WBO title in his second pro fight, but it remained vacant his loss.
"I thought my experience was the difference," Salido said. "He caught me with a very hard body shot late, and it was a matter of survival."
Lomachenko, 1-1 as a pro after going 397-1 as an amateur, earned an extra $15,000 for keeping the fight after Salido came in over the 126-pound class limit.
Salido kept his body close on Lomachenko, and aimed punches at the challenger's belt. He was cautioned on occasion to bring them up.
"I knew he would do that," Lomachenko said. ""It was a close fight. I box. I don't keep score."
Lomachenko showed little power through much of the fight, yet he kept it close with his boxing skill. But there were so many occasions that Lomachenko had to pull and push away from Salido that he used as much effort getting away as he did throwing punches.
Salido landed more power punches—137-105 according to CompuBox—and Lomachenko outjabbed Salido 59-5.