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Minnesota Twins' Kennys Vargas rounds the bases on a two-run home run off Chicago White Sox pitcher Scott Snodgress in the sixth inning of a baseball game, Wednesday, Sept. 3, 2014, in Minneapolis. (AP Photo/Jim Mone)

MINNEAPOLIS (AP) — Kennys Vargas homered for the second consecutive night and Eduardo Nunez had four hits as the Minnesota Twins defeated the Chicago White Sox 11-4 on Wednesday.

The Twins broke loose for five runs in the fifth inning to break a 3-all tie and set up Trevor May (1-4) for his first major league win. Vargas' RBI single and Eduardo Escobar's two-run triple did the bulk of the damage for Minnesota.

Vargas added a two-run homer deep into the second deck in left field in the sixth. Since being called up from the minors on Aug. 1, Vargas has 31 RBIs — third-most in the majors during that span.

May allowed three runs and six hits while striking out six in five innings.

Chicago White Sox pitcher John Danks throws against the Minnesota Twins in the first inning of a baseball game, Wednesday, Sept. 3, 2014, in Minneapolis.
Chicago White Sox pitcher John Danks throws against the Minnesota Twins in the first inning of a baseball game, Wednesday, Sept. 3, 2014, in Minneapolis. (AP Photo/Jim Mone) (Jim Mone/AP)

The Twins jumped out to a 3-0 lead in the first behind Nunez's RBI triple and back-to-back doubles from Josmil Pinto and Oswaldo Arcia.



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Chicago White Sox center fielder Adam Eaton dives to make the catch on a shallow pop fly off the bat of Minnesota Twins’ Aaron Hicks in the sixth
Chicago White Sox center fielder Adam Eaton dives to make the catch on a shallow pop fly off the bat of Minnesota Twins' Aaron Hicks in the sixth inning of a baseball game, Wednesday, Sept. 3, 2014, in Minneapolis. (AP Photo/Jim Mone) (Jim Mone/AP)

Chicago White Sox’s Paul Konerko, left, is presented with a large bottle of wine by Minnnesota Twins’ Joe Mauer, right, and Glen Perkins prior
Chicago White Sox's Paul Konerko, left, is presented with a large bottle of wine by Minnnesota Twins' Joe Mauer, right, and Glen Perkins prior to a baseball game, Wednesday, Sept. 3, 2014, in Minneapolis. It was part of honoring Konerko in his farewell baseball season. (AP Photo/Jim Mone) (Jim Mone/AP)

Chicago White Sox’s Paul Konerko acknowledges the crowd after he was presented a large bottle of wine by Minnnesota Twins’ Joe Mauer and Glen
Chicago White Sox's Paul Konerko acknowledges the crowd after he was presented a large bottle of wine by Minnnesota Twins' Joe Mauer and Glen Perkins prior to a baseball game, Wednesday, Sept. 3, 2014, in Minneapolis. It was part of honoring Konerko in his farewell baseball season. (AP Photo/Jim Mone) (Jim Mone/AP)